Drug Prescribing information

  • Usage & Indications
  • Preparation and Storage
  • Safety / contraindications

Usage & Indications

  • Blue Beam (methylene blue) Sterile injection USP, is indicated for the treatment of pediatric and adult patients with acquired methemoglobinemia
  • It may be prescribed by Doctor for off label use in Refractory Septic Shock, Urinary Tract Infections, as an antidote in Cyanide poisoning, as a medical dye for detection of Sentinel lymph modes and in gastric surgeries for detections of fistulas, and urinary leakage

Preparation and Storage

  • Blue Beam is hypotonic and may be diluted before use in a solution of 5% Dextrose in Water (D5W) in order to avoid local pain, particularly in the pediatric population. Use the diluted solution immediately after preparation.
  • Avoid diluting with sodium chloride solutions, because it has been demonstrated that chloride reduces the solubility of methylene blue.

Use in Specific Populations

  • Pregnancy and Lactation : Blue Beam may cause fetal harm when administered to a pregnant woman. Intra-amniotic injection of pregnant women with a methylene blue class product during the second trimester was associated with neonatal intestinal atresia and fetal death. Advise pregnant women of the potential risk to the fetus.
  • There is no information regarding the presence of methylene blue in human milk. Because of the potential for serious adverse reactions, including genotoxicity discontinue breast-feeding during and for up to 8 days after treatment
  • Renal Impairment Patients with any renal impairment should be monitored for toxicities and potential drug interactions for an extended period of time following treatment
  • Hepatic Impairment Methylene blue is extensively metabolized in the liver. Monitor patients with any hepatic impairment for toxicities and potential drug interactions for an extended period of time following treatment

Enquiries / Availability

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